Ketamine infiltration decreases the need for opioids after thyroid surgery

Background: Postoperative pain increases the risk of postoperative complications and may predispose patients to chronic post-surgical pain. This study aims evaluate impact ketamine wound infiltration versus placebo at end thyroid surgery on analgesic requirements. Methods: In this randomized controlled trial, we prospectively studied who underwent surgery. Patients were into two groups: group S, where local was performed using 10 ml a physiological saline solution; K, solution containing 2 mg/kg infiltrated. Standardized thyroidectomies in groups. Pain perception measured visual analog scale (VAS) every minutes post-anesthetic care unit (PACU) for hours thereafter 6 during first 24 hours. The opioid requirement PACU evaluated. A comparison between groups carried out. Results: Postoperatively, mean VAS higher S compared K all stay periods scores swallowing significantly lower 0, 10, 20 minutes. morphine consumption 0.71 mg 0 respectively (p=0.03). incidence nausea vomiting similar both Conclusions: Ketamine is an efficient modality reduce after surgery.